Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination.

@article{Sutton2001ManagingDP,
  title={Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination.},
  author={Mark D Sutton and Graham C Walker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 15},
  pages={8342-9}
}
Two important and timely questions with respect to DNA replication, DNA recombination, and DNA repair are: (i) what controls which DNA polymerase gains access to a particular primer-terminus, and (ii) what determines whether a DNA polymerase hands off its DNA substrate to either a different DNA polymerase or to a different protein(s) for the completion of the specific biological process? These questions have taken on added importance in light of the fact that the number of known template… CONTINUE READING

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