Management of severe recurrent focal segmental glomerulosclerosis through circulating soluble urokinase receptor modification.

Abstract

Circulating soluble urokinase receptor (suPAR) was recently identified as one of the causes responsible for native and recurrent focal segmental glomerulosclerosis (FSGS) through overactivation of podocyte β(3) integrin. Here, we discuss the management of a patient with very high suPAR serum levels and FSGS recurrence. The suPAR reduction using… (More)
DOI: 10.1097/MJT.0b013e3182811aca

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