Management of severe hyperkalemia

  title={Management of severe hyperkalemia},
  author={Lawrence S. Weisberg},
  journal={Critical Care Medicine},
  • L. Weisberg
  • Published 1 December 2008
  • Medicine
  • Critical Care Medicine
Background and Objectives:Hyperkalemia is one of the few potentially lethal electrolyte disturbances. Prompt recognition and expeditious treatment of severe hyperkalemia are expected to save lives. This review is intended to provide intensivists and other interested clinicians with an understanding of the pathophysiology that underlies hyperkalemia, and a rational approach to its management. Methods:This article reviews and analyzes literature relevant to the pathophysiology and management of… 
A narrative review over the literature using electronic databases as; MEDLINE, and EMBASE for studies involving data on Hyperkalemia management in emergency department, published in English language up to 2018 shows the importance of management and different approaches in ED.
Advances in diagnosis and management of hypokalemic and hyperkalemic emergencies.
The etiology, differential diagnosis, and diagnostic studies for detecting hypokalemia and hyperkalemia, including managing laboratory errors that lead to factitious potassium findings are discussed, with recommendations on criteria for disposition.
Management of Hyperkalemia: An Update for the Internist.
  • C. Kovesdy
  • Medicine, Biology
    The American journal of medicine
  • 2015
A physiologic-based approach to the treatment of acute hyperkalemia.
  • R. Shingarev, M. Allon
  • Medicine
    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2010
The present case highlights key physiologic mechanisms in the development of hyperkalemia and provides an outline for emergent treatment, and discusses specific mechanisms of action of available treatments of hyperKalemia.
Treatment and pathogenesis of acute hyperkalemia
This article focuses on the pathogenesis, clinical manifestations, and various treatment modalities for acute hyperkalemia and presents a systematic approach to selecting a treatment strategy.
Controversies in Management of Hyperkalemia.
Hyperkalemia management in the emergency department: An expert panel consensus
Information on available therapies for hyperkalemia is summarized and a hyperKalemia treatment algorithm for the ED practitioner is proposed based on the currently available literature and highlights diagnostic pitfalls and evidence gaps.
Incidental Hyperkalemia: An Unusual and Unexpected Case of Severe Hyperkalemia in an Otherwise Stable Post-Liver Transplant Recipient
A 68-year-old man in stable condition was found to have a serum potassium level of 7.9 mmol/L one year after an orthotopic liver transplant, and his hyperkalemia resolved with conventional therapy and adjustment of his medications.
Hyperkalemia: Recognition and Management of a Critical Electrolyte Disturbance
  • Ann Crawford
  • Medicine
    Journal of infusion nursing : the official publication of the Infusion Nurses Society
  • 2014
The pathophysiologic causes of hyperkalemia are reviewed and the manifestations, diagnostic tests, and various treatment options available to manage this electrolyte abnormality are discussed.


Hyperkalemia in Dialysis Patients
This article reviews extrarenal potassium homeostasis and its alteration in patients with end‐stage renal disease and pays particular attention to the factors that influence the movement of potassium across cell membranes.
Disorders of potassium homeostasis. Hypokalemia and hyperkalemia.
Hyperkalemia in hospitalized patients
An elevated serum potassium level in ahospitalized patient may be a marker for asignificantly increased risk of death, which is due tounderlying medical problems and is not a consequence of the hyperkalemia.
Digitalis intoxication; a review and report of forty cases, with emphasis on etiology.
The premise of this paper is to be sure that the patient has just enough digitalis, that he is neither underdigitalized nor toxic, and the need for careful follow-up of patients who are being digitalized.
Hyperkalaemia in patients in hospital.
A survey of all laboratory blood specimens with a plasma potassium concentration greater than or equal to 5.5 mmol/L was conducted over a three month period, finding that hyperkalaemia must always be considered seriously and regard given to the overall clinical status of the patient.
Retrospective review of the frequency of ECG changes in hyperkalemia.
There is no support for the poor sensitivity and specificity of electrocardiographic changes in guiding treatment of stable patients, and management of hyperkalemia should be guided by the clinical scenario and serial potassium measurements.
Nebulized albuterol for acute hyperkalemia in patients on hemodialysis.
In the doses used, nebulized albuterol therapy resulted in a prompt and significant decrease in the plasma potassium concentrations in patients on hemodialysis, and caused no adverse cardiovascular effects.
Signs and symptoms of electrolyte disorders.
The symptomatology of electrolyte disorders has much to do with changes in the behavior of excitable tissues, and Neurological disturbances are prominent, as are changes in cardiovascular function and in skeletal muscle.