Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review.

@article{McNicol2003ManagementOO,
  title={Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review.},
  author={Ewan D. McNicol and Nathalie C Horowicz-Mehler and Ruth A Fisk and Kyle F Bennett and Maria Gialeli-Goudas and Priscilla W Chew and Joseph Lau and Daniel Carr},
  journal={The journal of pain : official journal of the American Pain Society},
  year={2003},
  volume={4 5},
  pages={231-56}
}
Side effects can limit opioid dosage and reduce quality of life. The purpose of this systematic review was to assess the management of opioid side effects in the context of cancer pain management or, in the event that no evidence was available for cancer pain, for chronic noncancer pain. The side effects studied were constipation, pruritus, nausea and vomiting, myoclonus, sedation, respiratory depression, and delirium. Opioid rotation to manage side effects was also studied. For each side… CONTINUE READING

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