Management of muscle wasting in cancer-associated cachexia: understanding gained from experimental studies.

@article{Baracos2001ManagementOM,
  title={Management of muscle wasting in cancer-associated cachexia: understanding gained from experimental studies.},
  author={Vickie Baracos},
  journal={Cancer},
  year={2001},
  volume={92 6 Suppl},
  pages={
          1669-77
        }
}
BACKGROUND Cancer-associated cachexia is a syndrome of progressive wasting of body energy (adipose) and protein (skeletal muscle) reserves. Cachexia occurs in a majority of advanced cancer patients. Extensive loss of muscle mass is one factor likely to be associated with fatigue in cancer patients. METHODS Research with animal models of cancer-associated cachexia that have focused on the processes of muscle protein synthesis and degradation are reviewed in this article. Modulation of the… CONTINUE READING

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