Management of localized prostate cancer in senior adults: the crucial role of comorbidity

@article{Fitzpatrick2008ManagementOL,
  title={Management of localized prostate cancer in senior adults: the crucial role of comorbidity},
  author={John M. Fitzpatrick},
  journal={BJU International},
  year={2008},
  volume={101}
}
Prostate cancer is predominantly a disease of senior adults, i.e. those aged >70 years. With the increasing life expectancy worldwide, the burden of prostate cancer in senior adults is expected to increase. 
Prostate cancer in the elderly
The objectives of this study were to determine the frequency of metastatic (M1) prostate cancer (PC) at presentation in different age groups, to examine the association of age with PC‐specificExpand
Cause of Death in Older Men After the Diagnosis of Prostate Cancer
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Prostate Cancer in Seniors: Part 1: Epidemiology, Pathology, and Screening.
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Can we avoid surgery in elderly patients with renal masses by using the Charlson comorbidity index?
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Laparoscopic radical prostatectomy is feasible and effective in ‘fit’ senior men with localized prostate cancer
Study Type – Therapy (case series)
Level of Evidence 4
Prostate cancer in the elderly.
TLDR
There is a need for more risk stratified approaches for the management of prostate cancer in the elderly to avoid unnecessary intervention in men who unlikely benefit from such intervention, and allow treatment in those who might benefit from it. Expand
Impact of age at diagnosis on prostate cancer treatment and survival.
TLDR
Findings support making decisions regarding treatment on the basis of disease risk and life expectancy rather than on chronologic age, as older patients are more likely to have high-risk prostate cancer at diagnosis and less likely to receive local therapy. Expand
Older Men with Intermediate to High Risk Prostate Cancer-Patterns of Care and Outcomes of Treatment
TLDR
The oldest patients with prostate cancer do just as well as younger patients with any given treatment modality, and have similar cancer specific survival with hormone therapy as they do with radiation or surgery. Expand
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