Management of laryngopharyngeal reflux: an unmet medical need

  title={Management of laryngopharyngeal reflux: an unmet medical need},
  author={Frank Zerbib and David Stoll},
  journal={Neurogastroenterology \& Motility},
Abstract  Laryngopharyngeal reflux (LPR) is defined by the association of laryngeal symptoms with laryngeal inflammation at laryngoscopy. However, these symptoms are difficult to characterize and the laryngoscopic signs lack specificity. Moreover, to date, the diagnosis of LPR can rely neither on esophageal investigations (endoscopy, pH/impedance monitoring) nor on response to high dose proton pump inhibitors because of a high placebo effect. Therefore, there is a need for the development of… 

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The aims of the study were to determine the prevalence of high esophageal acid exposure time (AET) in patients presenting with cough or LPS and determine the incremental yield of multichannel intraluminal impedance–pH (MII‐pH) monitoring.

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Throat Clearing, Frequently Reported, But is it GERD Related?

Although TC is often considered a possible GERD-related symptom, it is found to have a low probability of objective association and should not be considered as a GERD symptom, even as an atypical one.

Reflux Episode Reaching the Proximal Esophagus Are Associated with Chronic Cough

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Combined Dual Channel Impedance/pH-metry in Patients With Suspected Laryngopharyngeal Reflux

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Laryngopharyngeal Reflux: Position Statement of the Committee on Speech, Voice, and Swallowing Disorders of the American Academy of Otolaryngology-Head and Neck Surgery

Gastroesophageal reflux disease (GERD) is a clinical term that refers to GER that is excessive and that causes tissue damage and/or clinical symptoms (eg, heartburn).

Evaluation and management of laryngopharyngeal reflux.

Laryngopharyngeal reflux should be suspected when the history and laryngoscopy findings are suggestive of the diagnosis and the addition of multichannel intraluminal impedance technology improves diagnostic accuracy for describing LPR events.

Surgical fundoplication in laryngopharyngeal reflux unresponsive to aggressive acid suppression: a controlled study.

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    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2006

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ACG Practice Guidelines: Esophageal Reflux Testing

Guidelines for esophageal reflux testing are developed under the auspices of the American College of Gastroenterology and its Practice Parameters Committee and approved by the Board of Trustees.

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Meta‐analysis: the efficacy of proton pump inhibitors for laryngeal symptoms attributed to gastro‐oesophageal reflux disease

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