Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab

@article{Elter2008ManagementOI,
  title={Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab},
  author={Thomas Elter and Janne J. Vehreschild and John G Gribben and Oliver A Cornely and Andreas Engert and Michael J Hallek},
  journal={Annals of Hematology},
  year={2008},
  volume={88},
  pages={121-132}
}
Infection is a significant cause of morbidity and death in patients with chronic lymphocytic leukemia (CLL). Increased infectious events may arise from the multiple courses of immunosuppressive therapy and progressive deterioration of a patient’s immune system over the course of disease. The humanized, anti-CD52 monoclonal antibody alemtuzumab (Campath or Campath-1H) has shown notable activity for both untreated and fludarabine-refractory CLL. The antibody not only targets malignant cells but… CONTINUE READING

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