Management of diabetes insipidus in children

  title={Management of diabetes insipidus in children},
  author={Garima Mishra and Sudha Rao Chandrashekhar},
  booktitle={Indian journal of endocrinology and metabolism},
Diabetes Insipidus (DI) is a heterogeneous clinical syndrome of disturbance in water balance, characterized by polyuria (urine output > 4 ml/kg/hr), polydypsia (water intake > 2 L/m(2)/d) and failure to thrive. In children, Nephrogenic DI (NDI) is more common than Central DI (CDI), and is often acquired. The signs and symptoms vary with etiology, age at presentation and mode of onset. Neonates and infants with NDI are severely affected and difficult to treat. Diagnosis is based on the presence… CONTINUE READING


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