Management of cutaneous viral warts

@article{Lynch2014ManagementOC,
  title={Management of cutaneous viral warts},
  author={Magnus D Lynch and Jane Cliffe and Rachael Morris-Jones},
  journal={BMJ : British Medical Journal},
  year={2014},
  volume={348}
}
#### Summary points The prevalence of cutaneous viral warts in the general population is estimated to be 7-12%. Many patients present to primary care with pain and discomfort along with other concerns, such as cosmetic appearance. Although cutaneous viral warts are ubiquitous, no definitive treatment exists. Nevertheless, most warts resolve spontaneously and a large proportion of the remainder respond to simple recommended treatment. For these reasons, potential treatments must have minimal… 
View on BMJ
bmj.com
51 Citations
Highly Influential Citations
2
Background Citations
13
Methods Citations
1

51 Citations

Citation Type

Citation Type

Treatment of cutaneous viral warts in children: A review
TLDR
There is evidence that salicylic acid and cryotherapy are effective, and although cryotherapy is more effective, there is a higher risk of side effects such as pain and blistering.
Plantar Warts: Epidemiology, Pathophysiology, and Clinical Management
TLDR
Given the high propensity for treatment resistance of plantar warts and no established, practical, and reliable method of prevention, HPV prophylaxis for populations that demonstrate high rates of plantAR warts may be of benefit in controlling the spread of lesions.
Evaluation of the Efficacy of Acitretin in the Treatment of Multiple Viral Warts: A Pilot Study
TLDR
Patients with recalcitrant multiple warts respond favourably to the safe, effective, and well-tolerated treatment with acitretin, according to the ideal model.
ROLE OF SYSTEMIC RETINOIDS IN THE TREATMENT OF WARTS
TLDR
Systemic retinoids are effective in the treatment of warts and they are well tolerated, non-invasive alternative modalities with few adverse effects.
THE EFFICACY OF CERVARIX VACCINE IN WART TREATMENT: UPDATED MANAGEMENT
TLDR
The mechanism of action of HPV vaccines in the treatment of warts is not yet established, but might be mediated by the development of IgG neutralizing antibodies directed against the major and minor capsid proteins, L1 and L2 of human papillomavirus generated as a result of vaccination.
The status of treatment for plantar warts in 2021: No definitive advancements in decades for a common dermatology disease.
Evaluation of therapeutic effectiveness of vitamin D3 injections in common warts in a tertiary care centre
TLDR
Intralesional Vit D3 injections may be a treatment option for warts, which has a good cosmetical acceptance and simple, well tolerated easily administrated in outpatient clinic rather than conventional treatment.
Immunotherapy of viral warts: myth and reality
TLDR
Among the available options for treatment of warts, none is uniformly effective or viricidal and thus the reproducibility of many of the listed treatments is difficult to evaluate and a possible placebo effect cannot be ruled out.
THE COMPARISON STUDY OF 5 FLUOROURACIL VS. CRYOTHERAPY IN THE TREATMENT OF THE BACKHAND RESISTANT COMMON WART
TLDR
Comparison of therapeutic effects of 5 Fluorouracil with cryotherapy in treatment of common warts of backhand shows appropriate therapeutic response in addition to lower rates of relapse and complications by 5 FU treatments can make a major change and lower the psychosocial burden of this disease dramatically.
Efficacy of intralesional Candida antigen immunotherapy in treatment of recalcitrant warts.
TLDR
Intralesional Candida antigen immunotherapy is a safe, promising and efficient treatment approach for recalcitrant warts.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 38 REFERENCES
Topical treatments for cutaneous warts.
TLDR
There is a considerable lack of evidence on which to base the rational use of topical treatments for common warts, and the best available evidence was for simple topical treatments containing salicylic acid, which were clearly better than placebo.
Systemic treatments for cutaneous warts: A systematic review
TLDR
Reviewed trials of systemic treatments for cutaneous warts were highly variable in methods and quality, and there was a paucity of evidence from randomized, placebo-controlled trials on which to base the rational use of such therapies.
Efficacy of Imiquimod 5% Cream in the Treatment of Recalcitrant Warts in Children
TLDR
It is demonstrated that the topical application of imiquimod 5% cream is an effective treatment for long‐lasting cutaneous warts in children.
Treatment of genital warts with an immune-response modifier (imiquimod).
Recalcitrant viral warts treated by diphencyprone immunotherapy
TLDR
DCP immunotherapy is an effective option for the treatment of recalcitrant viral warts but patients must be motivated to attend for sequential applications and must be warned about potential uncomfortable side‐effects.
Outcome of carbon dioxide laser therapy for persistent cutaneous viral warts
TLDR
The use of the CO2 laser may clear otherwise resistant viral warts but a significant morbidity may occur with this method of treatment.
Intralesional immunotherapy of warts with mumps, Candida, and Trichophyton skin test antigens: a single-blinded, randomized, and controlled trial.
TLDR
Intralesional immunotherapy using injection of Candida, mumps, or Trichophyton skin test antigens is an effective treatment for warts, as indicated by significantly higher response rates and distant response rates in subjects receiving antigen.
Treatment of extensive and recalcitrant viral warts with acitretin
45 Correspondence Toxic epidermal necrolysis caused by tetrazepam A 50-year-old man was referred to our department with toxic epidermal necrolysis (TEN). He had a history of Stevens– Johnson syndrome…
An open label evaluation of the efficacy of imiquimod 5% cream in the treatment of recalcitrant subungual and periungual cutaneous warts
TLDR
Topical imiquimod 5% cream is an interesting novel treatment for multiple periungual and subungual warts and its tolerability is excellent when compared to other commonly used modalities and there are few side effects.
An assessment of methods of treating viral warts by comparative treatment trials based on a standard design
TLDR
The variation in response to treatment was shown to be influenced significantly by factors including age, type, number and duration of warts, and the level of cure to depend on the proportions of the various response groups within the population under consideration.
...
1
2
3
4
...