Management of colorectal cancer: a role for genetics in prevention and treatment?

  title={Management of colorectal cancer: a role for genetics in prevention and treatment?},
  author={Neel Sengupta and Kathryn A Gill and Tammie S MacFie and Cecilia S. L. Lai and Nirosha Suraweera and Sarah Mcdonald and Andrew Silver},
  journal={Pathology, research and practice},
  volume={204 7},
Colorectal cancer remains one of the most common cancers in the Western world and amongst the top three causes of cancer morbidity and death. Cancer is caused by genetic mutations, but currently there is little use of genetic information in the clinic with the exception of establishing germline mutations for the uncommon predisposing syndromes. Rapid advances in technologies allowing high throughput analysis of germline and somatic mutations raises the possibility that genetics will find a… CONTINUE READING


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