Management of chronic immune thrombocytopenic purpura in children and adults.

@article{Blanchette1998ManagementOC,
  title={Management of chronic immune thrombocytopenic purpura in children and adults.},
  author={Victor S. Blanchette and John T. Freedman and Bernadette M Garvey},
  journal={Seminars in hematology},
  year={1998},
  volume={35 1 Suppl 1},
  pages={36-51}
}
Chronic immune thrombocytopenic purpura (ITP) is characterized by macrophage destruction of platelets, primarily in the spleen, and occurs in both adults and children. Historically, splenectomy is often required, especially in adults with chronic ITP; however, several medical options have been used successfully prior to splenectomy or when this procedure has either failed or been refused by the patient. These include corticosteroids, intravenous immunoglobulin (IVIg), intravenous anti-D… CONTINUE READING

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