Management of chronic cough

@article{Pavord2008ManagementOC,
  title={Management of chronic cough},
  author={Ian D. Pavord and Kian Fan Chung},
  journal={The Lancet},
  year={2008},
  volume={371},
  pages={1375-1384}
}

Figures and Tables from this paper

Controversies in the evaluation and management of chronic cough.
  • S. Birring
  • Medicine
    American journal of respiratory and critical care medicine
  • 2011
TLDR
There is a pressing need to understand the genetic, molecular, and physiological basis of unexplained chronic cough and to develop novel antitussive drugs that down-regulate cough reflex sensitivity.
Management of chronic refractory cough
TLDR
Treatment options include speech pathology interventions using techniques adapted from the treatment of hyperfunctional voice disorders, as well as the use of centrally acting neuromodulators such as gabapentin and pregabalin.
Diagnosis and management of chronic cough: similarities and differences between children and adults
TLDR
In adults, asthma and bronchitis are well-defined etiologies of chronic cough, but much chronic cough in adults is largely a conundrum.
New concepts in the management of chronic cough.
  • S. Birring
  • Medicine
    Pulmonary pharmacology & therapeutics
  • 2011
The never-ending challenge of chronic cough in adults
TLDR
This review summarizes the current evidence on the aetiology and the diagnostic difficulties of chronic cough in adults, and provides an algorithmic approach, along with practical tips, for its management by the busy practicing clinician.
Cough hypersensitivity syndrome: towards a new approach to chronic cough
TLDR
It has been proposed that chronic cough is the result of an interaction between intrinsic cough reflex abnormalities and aggravating factors such as angiotensin-converting enzyme (ACE) inhibitors, gastro-oesophageal reflux disease (GORD), upper airway disorders, eosinophilic airway diseases and cigarette smoke/chronic obstructive pulmonary disease (COPD).
Cough: a worldwide problem.
Cough Hypersensitivity Syndrome – A Major Advance in the Understanding of Chronic Cough
TLDR
In an expert interview, Professor Kian Fan Chung of the National Heart & Lung Institute, Imperial College and the Royal Brompton & Harefield NHS Trust, London, UK, discusses CHS and the recent advances in understanding of this condition that is leading to the development of novel treatment approaches.
Cough: an unmet clinical need
TLDR
Chronic, refractory unexplained cough must be distinguished from cough that has not been fully evaluated and treated according to current guideline recommendations, and new safe and effective anti‐tussive agents for use when cough suppression is desired, regardless of underlying aetiology of cough.
Chronic cough: what's new in the diagnostic protocol and management?
TLDR
Management of chronic cough needs new approaches that are easier to carry out and implement, and the empirical trials of therapy, as developed on the probability of causes of Chronic cough, and combined with a few common tests, is easy to practice.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 124 REFERENCES
Chronic cough: a rational approach to investigation and management
  • I. Pavord
  • Medicine
    European Respiratory Journal
  • 2005
TLDR
The investigation protocol is based on the view that most cases of nonasthmatic chronic cough are caused by rhinosinusitus and/or gastro-oesophageal reflux, and the protocol has largely stood the test of time.
Recommendations for the management of cough in adults
TLDR
The British Thoracic Society Standards of Care Committee agreed to the development of a Working Group tasked with the job of producing a set of guidelines for the management of cough with the following key objectives.
Chronic idiopathic cough: a discrete clinical entity?
TLDR
Patients with CIC commonly describe a URTI that initiates their cough, which then lasts for many years, and they demonstrate an exquisitely sensitive cough reflex, suggesting that CIC may be a distinct clinical entity with an as-yet unidentified underlying pathology.
A systematic evaluation of mechanisms in chronic cough.
TLDR
It is concluded that chronic cough is a nonspecific symptom that is associated with several apparently unrelated mechanisms, including UAHR, somatization, BHR, and eosinophilic bronchitis.
The diagnosis and treatment of cough.
TLDR
An approach to managing cough in adults with a systematic approach based on the guidelines described should be possible to diagnose and treat cough successfully in the great majority of cases.
Investigation and management of chronic cough using a probability-based algorithm
TLDR
Use of the algorithm resulted in identification of the cause of cough and successful treatment in the large majority of cases, and has the potential to improve management by providing a structured approach, reducing the number of investigations performed, and minimising unnecessary delays in treatment.
Eosinophilic bronchitis: an imortant cause of prolonged cough
The recent development of noninvasive techniques to measure airway inflammation has led to the recognition of eosinophilic bronchitis, a condition characterized by a sputum eosinophilia identical to
Chronic cough with a history of excessive sputum production. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy.
TLDR
The anatomic diagnostic protocol for cough is also valid for CCS and the major causes of chronic excessive sputum production and chronic cough are so similar that CCS should be considered a form of chronic cough.
Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines.
TLDR
This revision of cough guidelines more narrowly focuses the guidelines on the diagnosis and treatment of cough, the symptom, in adult and pediatric populations, and minimizes the discussion of cough as a defense mechanism.
A pathogenic triad in chronic cough: asthma, postnasal drip syndrome, and gastroesophageal reflux disease.
TLDR
It is essential to consider pulmonary and extrapulmonary causes in order to prescribe a successful specific therapy for chronic cough, and the expression "pathogenic triad of chronic cough" should be acknowledged in specialized literature.
...
1
2
3
4
5
...