Management of carotid artery disease in the high-risk patient with emphasis on the SAPPHIRE study.

@article{Rajagopal2007ManagementOC,
  title={Management of carotid artery disease in the high-risk patient with emphasis on the SAPPHIRE study.},
  author={Vivek Rajagopal and Jay Brijesh S. Yadav},
  journal={Current cardiology reports},
  year={2007},
  volume={9 1},
  pages={20-4}
}
Ischemic stroke threatens public health dramatically, and demographic changes promise to continue this epidemic. Although medical advances in risk factor modification, hypertensive control, and antiplatelet therapy have mitigated morbidity and mortality of cerebrovascular disease somewhat, stroke still costs billions in healthcare dollars and reduces quality of life for many patients immeasurably. Carotid endarterectomy has been the standard for invasive management of carotid atherosclerosis… CONTINUE READING