Management of bleeding complications in the anticoagulated patient.

  title={Management of bleeding complications in the anticoagulated patient.},
  author={Vinai C. Bhagirath and Lauren O'Malley and Mark Andrew Crowther},
  journal={Seminars in hematology},
  volume={48 4},
As new anticoagulants become available, and the number of anticoagulated patients continues to rise, it is necessary to know how to deal with associated bleeding complications. In this review, reversal strategies for traditional anticoagulants (warfarin and heparin) as well as newer anticoagulants are described. Prothrombin complex concentrates (PPCs) can be used to reverse vitamin K antagonists (VKA), and plasma may be used where they are not available. Recombinant activated factor VII (rFVIIa… CONTINUE READING