Management of benzodiazepine-resistant alcohol withdrawal across a healthcare system: Benzodiazepine dose-escalation with or without propofol.

@article{Wong2015ManagementOB,
  title={Management of benzodiazepine-resistant alcohol withdrawal across a healthcare system: Benzodiazepine dose-escalation with or without propofol.},
  author={Adrian Wong and Neal J. Benedict and Brian R Lohr and Anthony F. Pizon and Sandra L. Kane-Gill},
  journal={Drug and alcohol dependence},
  year={2015},
  volume={154},
  pages={296-9}
}
BACKGROUND Severe cases of alcohol withdrawal syndrome (AWS) may not resolve despite escalating doses of benzodiazepines (BZDs). Benzodiazepine-resistant alcohol withdrawal (RAW) is a subset of severe alcohol withdrawal defined by the requirement of ≥40mg of diazepam administered within one hour. Use of adjunct agents, such as propofol, may be beneficial to minimize BZD adverse effects and improve symptom control. While limited evidence suggests propofol as an effective adjunct in AWS through… CONTINUE READING

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Benzodiazepine - resistant alcohol withdrawal ( RAW ) is a subset of severe alcohol withdrawal defined by the requirement of ≥40 mg of diazepam administered within one hour .
BenzodiazepinesChemical structure ofDiazepam
Benzodiazepine - resistant alcohol withdrawal ( RAW ) is a subset of severe alcohol withdrawal defined by the requirement of ≥40 mg of diazepam administered within one hour .
Benzodiazepine - resistant alcohol withdrawal ( RAW ) is a subset of severe alcohol withdrawal defined by the requirement of ≥40 mg of diazepam administered within one hour .
Benzodiazepine - resistant alcohol withdrawal ( RAW ) is a subset of severe alcohol withdrawal defined by the requirement of ≥40 mg of diazepam administered within one hour .
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