Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance

@article{Visintin2010ManagementOB,
  title={Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance},
  author={Cristina Visintin and Moira A. Mugglestone and Ella Fields and Paul Brian Jacklin and M Stephen Murphy and Andrew J. Pollard},
  journal={BMJ : British Medical Journal},
  year={2010},
  volume={340}
}
Bacterial meningitis and meningococcal septicaemia in children and young people are associated with considerable mortality and morbidity. Case fatality rates vary according to the causative organism and the age of the child or young person. In the United Kingdom they range from 2% to 11% and are especially high (about 10%) in neonates (children younger than 28 days). Survivors of bacterial meningitis and meningococcal septicaemia may experience serious long term morbidities (box 1). This… 

Should corticosteroids be used in bacterial meningitis in children?

Long-Term Sequelae of Childhood Bacterial Meningitis

TLDR
Recent evidence on the morbidity faced by childhood survivors of bacterial meningitis is reviewed, with consistently high levels of complications described in the literature calling for more widespread vaccination programs for prevention and a greater focus on potential complications by educators and health-care providers to support childhood survivors.

Diagnosis and Management of Bacterial Meningitis in the Paediatric Population: A Review

TLDR
The changing epidemiology of the disease, current diagnostic techniques as well as controversies and advances in the management of bacterial meningitis in the paediatric population are outlined.

Clinical presentation of meningococcal disease in childhood.

TLDR
The availability of new vaccines able to cover the emerging serotypes including A and Y as well as the availability on the market of new products that could prevent meningococcal B infection represent a great opportunity for the decrease of the burden of this complicated disease.

Meningococcal disease: a case report and discussion of clinical presentation and management

TLDR
A patient who presented withMeningococcal shock associated with characteristic skin lesions of meningococcemia is presented and the importance of early identification of the characteristic skin injuries and timely institution of appropriate antibiotic therapy is emphasized.

Invasive Meningococcal Disease: A Review

TLDR
It is important to be able to correctly recognize patients withasive meningococcal disease for early and aggressive management and prevention by vaccination remains the best public health measure to tackle this deadly infection.

The golden hours in paediatric septic shock--current updates and recommendations.

TLDR
The use of early goal-directed therapy has had significant impact on patient outcomes and protocolised resuscitation of children in septic shock is recommended.
...

References

SHOWING 1-10 OF 12 REFERENCES

Bacterial meningitis and meningococcal septicaemia:the management of bacterial meningitis and meningococcal septicaemia in children and young people younger than 16 years in primary and secondary care

TLDR
A clinical guideline on meningitis and meningococcal disease in children and young people for use in the NHS in England and Wales is developed following referral of the topic by the Department of Health.

Neonatal meningitis in England and Wales: 10 years on

TLDR
Although the incidence of neonatal meningitis in England and Wales remains unchanged, mortality from this infection has fallen significantly and if this improvement is maintained as reflected in the level of sequelae at 5 years of age, then the fear surroundingMeningitis during the neonatal period will have been dramatically reduced.

Guidelines for public health management of meningococcal disease in the UK.

  • Medicine
    Communicable disease and public health
  • 2002
TLDR
These guidelines cover pre-admission management, investigation of suspected cases, the role of public health, public health action after a single case, prophylaxis in healthcare settings, and management of clusters.

Changing patterns of case ascertainment and trends in meningococcal disease in England and Wales.

TLDR
The data suggest that reporting practice changed between 1989 and 1995 and that the ascertainment of clinically diagnosed disease improved, particularly for meningococcal septicaemia, and the role of non-culture diagnosis will be crucial in enhancing surveillance based on clinical diagnoses.

Towards an improved serogroup B Neisseria meningitidis vaccine

TLDR
The future prevention of serogroup B disease will rely on both outer membrane vesicle vaccines being used for serosubtype-specific outbreaks and new vaccines containing multiple other antigens.

One-Year Experience with Day-of-Surgery Pregnancy Testing Before Elective Orthopedic Procedures

TLDR
A policy of routinely performing urine hCG pregnancy tests in women of childbearing age on the day of surgery was effective in detecting unrecognized pregnancy and resulted in a postponement of elective surgery in all cases.

Natural limits of pregnancy testing in relation to the expected menstrual period.

TLDR
The highest possible screening sensitivity for an hCG-based pregnancy test is estimated to be 90% (95% confidence interval [CI], 84%-94%) on the first day of the missed period, while an even larger percentage of clinical pregnancies may be undetected by current test kits on this day, given their reported assay properties and other practical limitations.