Management of acyclovir-resistant herpes simplex virus.

  title={Management of acyclovir-resistant herpes simplex virus.},
  author={Suneel Chilukuri and Ted Rosen},
  journal={Dermatologic clinics},
  volume={21 2},
In immunocompetent patients, HSV is controlled rapidly by the human host's immune system, and recurrent lesions are small and short lived. When treated with antiviral agents, these patients rarely develop resistance to these drugs. In contrast immunocompromised patients might not be able to control HSV infection. Thus, frequent and severe reactivations are often seen and might lead to fatal herpetic encephalitis or disseminated HSV infection. Treatment in these patients is limited because… CONTINUE READING


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