Management of Vasospastic Disorders with Botulinum Toxin A

@article{VanBeek2007ManagementOV,
  title={Management of Vasospastic Disorders with Botulinum Toxin A},
  author={Allen L. Van Beek and Paul K Lim and Andrew Le Gear and Marc R. Pritzker},
  journal={Plastic and Reconstructive Surgery},
  year={2007},
  volume={119},
  pages={217-226}
}
Background: Surgical digital artery sympathectomy is indicated when medical management has failed to control rest pain, impending infarction of digits, or healing of ischemic ulcerations caused by profound vasospasm that is associated with other systemic diseases. After digital artery sympathectomy, recurrence or persistence of vasospasm may compromise hand function and ultimately result in amputation of all or portions of both lower and upper extremities. Methods: The authors present a case… Expand
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Botox Therapy for Ischemic Digits
TLDR
Vascular function is abnormal in patients with Raynaud's phenomenon and Botox yielded a distinct improvement in perfusion and reduction in pain in patients failing conservative management, although its mechanism is unknown. Expand
Botulinum toxin type A: a treatment option for digital ischemia in patients with Raynaud's phenomenon.
TLDR
Botulinum toxin type A significantly improves pain and improves healing in Raynaud's patients with few complications and BTX-A was found to be a safe and useful treatment option for vasospastic digital ischemia. Expand
The Effects of Botulinum Toxin A on Pain in Ischemic Vasospasm.
TLDR
Botulinum toxin type A administration can result in rapid and sustained pain relief for several months with a reduction in opioid prescriptions and improve patient-reported disability for 6 months. Expand
Botulinum Toxin A Salvage of Ischemic Hand Trauma.
TLDR
In the acute traumatic vascular hand injury, early Botox injection markedly increases digital salvage; direct nerve effects after Botox injections improve postinjury pain scores; and early use of Botox in finger injuries is the standard approach to impending ischemia in the hand. Expand
Botulinum Toxin A Treatment for Primary and Secondary Raynaud's Phenomenon in Teenagers.
TLDR
BTX injection is a simple, noninvasive, and cost-effective treatment alternative, offering an important nonsurgical therapeutic option for the pediatric population, and could also help optimize the dose of other treatments used in these patients. Expand
Botulinum toxin type A treatment for Raynaud’s phenomenon and other novel dermatologic therapeutic applications
TLDR
Amelioration of pain improves hand function despite occasional muscle weakness and favorable changes of improved perfusion are quantified using visual analogue scale (VAS) and confirmed by digital surface temperature readings. Expand
Botulinum toxin for Raynaud's phenomenon: an useffull but seldom reminded therapy for severe cases
Introduction: Raynaud's phenomenon (RP) is an exaggerated physiological response of the extremity vessels, mainly to cold and stress. Patients refractory to clinical treatment or intolerant to its… Expand
Recent advances for the management of Raynaud phenomenon using botulinum neurotoxin A.
TLDR
The potential treatment of Raynaud phenomenon using botulinum neurotoxin A (BoNT-A) is reviewed, which results in digital ischemia, which can preispose the patient to occlusive disease with ulcers nd gangrene. Expand
The role of botulinum toxin in vasospastic disorders of the hand.
TLDR
Botulinum toxin has been shown to be an effective alternative to surgery, with a single treatment being capable of resolving pain and healing ulcer. Expand
The Role of Botulinum Toxin A in the Treatment of Raynaud Phenomenon
TLDR
Botulinum neurotoxin-A injection proved to be a valid approach in both primary and secondary RP, and the available evidence shows the achievement of both symptomatic and functional improvements in this debilitating condition. Expand
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