Management of Sinusitis in Adult Cystic Fibrosis

  title={Management of Sinusitis in Adult Cystic Fibrosis},
  author={Steven C. Marks and Dana G Kissner},
  journal={American Journal of Rhinology \& Allergy},
  pages={11 - 14}
  • S. Marks, D. Kissner
  • Published 1 January 1997
  • Medicine
  • American Journal of Rhinology & Allergy
Until recently, cystic fibrosis was frequently fatal during childhood. However, with current medical management, many patients are living into adulthood. This has created a new population of patients with chronic sinusitis and severe medical problems. In this report, experience with 22 patients, eight of whom have undergone sinus surgery, is presented, and recommendations for management are proposed. Presenting symptoms are typical of sinusitis, but in a few patients, severe debilitating… 
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A review of endoscopic sinus surgery in patients with cystic fibrosis shows a complication rate of 11.5%, which compares favorably with the non-CF ESS complication rates reported in the literature.
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It is concluded that functional endoscopic sinus surgery has been an effective tool in treating pediatric sinusitis refractory to medical therapy, with postoperative care recognized as having utmost importance to bridge surgical therapy with continued medical treatment for pediatric chronic rhinosinusitis.
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Lung transplantation for cystic fibrosis: current concepts and one center's experience.
Lung transplant should be offered to all patients with advanced CF lung disease if they meet currently accepted inclusion and exclusion criteria and can improve quality of life.
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and "mouthing shared toys" and the other variables in their study to support their theories. So, after much discussion and disagreement, have we reached a conclusion about smoking and middle ear
Perioperative Strategies to Improve Sinus Surgery Outcomes in Patients with Cystic Fibrosis
  • D. Crockett, K. Wilson, J. Meier
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2013
Despite the prevalence of recurrent sinonasal disease after FESS in patients with CF, evidence for definitive perioperative management in this population is lacking.


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The otolaryngologic manifestations of CF, based on a retrospective analysis of 450 cases, included Nasal polyposis and sinusitis occurred in 10% and 11% of patients, respectively, and polypectomy was, after laparotomy, the most common surgical procedure these children underwent.
Nasal and Paranasal Sinus Surgery in Children with Cystic Fibrosis
Management of 40 children with cystic fibrosis who underwent nasal polypectomy, intranasal ethmoidectomy, and Caldwell-Luc procedures to treat extensive sinusitis and nasal polyposis forms the basis for this report.
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A 20‐year retrospective study of children with cystic fibrosis revealed 39 children developed nasal polyps and these children required 85 nasal polypectomies and over 95% of these CF children were able to return home in less than 48 hours, and extensive hospital stays appeared to be required.
Nasal polyps and sinusitis in children with cystic fibrosis.
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  • Otolaryngol Head Neck Surg 97:356--360,
  • 1987
Pathology in Fibrocystic Disease of the Pancreas
  • Heineman Medical Books,
  • 1952