Management of Chemotherapy-Induced Alopecia With Scalp Cooling.

@article{Kruse2018ManagementOC,
  title={Management of Chemotherapy-Induced Alopecia With Scalp Cooling.},
  author={Megan L. Kruse and Jame Abraham},
  journal={Journal of oncology practice},
  year={2018},
  volume={14 3},
  pages={
          149-154
        }
}
Chemotherapy-induced alopecia is a common and distressing adverse effect of many types of chemotherapy. Scalp cooling has been used since the 1970s for prevention of chemotherapy-induced alopecia; however, most data regarding this treatment modality are retrospective in nature, and use in the United States has been limited by safety concerns, specifically the potential for scalp metastases. Two prospective studies of scalp-cooling systems performed in the United States were published within the… 
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Safety and efficacy of scalp cooling system in preventing chemotherapy induced alopecia - A single center prospective study.
Effect of Using a Cold Cap on Chemotherapy- Induced Hair Loss in Patients with Breast Cancer
TLDR
Using a cold cap while receiving chemotherapy for breast cancer is effective in preventing hair loss, according to the results of a randomized Clinical Trial.
A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia
TLDR
BPM31543 applied topically twice daily to the scalp is safe and well tolerated in patients receiving taxane-based chemotherapy and warrants further investigation in Phase 2/3 trials.
Does hair curl variation influence the efficacy of scalp cooling in the prevention of chemotherapy-induced alopecia in breast cancer patients? A randomised pilot trial
TLDR
This study suggests that hair curvature has no significant impact on the efficacy of scalp cooling to reduce CIA, however, this requires confirmation.
The scalp cooling therapy for hair loss in breast cancer patients undergoing chemotherapy: a systematic review and meta-analysis
TLDR
It is shown that scalp cooling devices can significantly improve the patients with breast cancer chemotherapy–induced alopecia, but the implications of its side effects provide guide for the implementation of this technology.
Digital Innovation in Oncological Primary Treatment for Well-Being of Patients: Psychological Caring as Prompt for Enhancing Quality of Life
TLDR
The data evidenced the need to implement a supportive clinical approach via brief, tailored psychological intervention addressing patients’ progressive adaptation to chemotherapy adverse events and their concerns regarding induced alopecia and the value of the scalp cooling system.
Dermatologic conditions in women receiving systemic cancer therapy☆
Integration of Physician and Nursing Professional Efforts to Deliver Supportive Scalp Cooling Care to Oncology Patients at Risk for Alopecia
TLDR
A pragmatic workflow for collaborative efforts from physicians and allied health professionals in the USA to deliver supportive SC to reduce CIA in patients undergoing treatment regimens known to impact hair follicles is presented.
Management of dermatologic adverse events from cancer therapies: recommendations of an expert panel☆☆☆
Nursing Outcomes of Patient’s Comfort during Neoplastic Chemotherapy: An Integrative Review
TLDR
Nursing outcomes of the patients’ comfort after receiving chemotherapy should be led by the patient’s quality of life and satisfaction, and include the management not only of the physical symptoms and treatment-related side effects, but also the changes in a patient's emotional status and daily lives.
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References

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TLDR
Among women undergoing non–anthracycline-based adjuvant chemotherapy for early-stage breast cancer, the use of scalp cooling vs no scalp cooling was associated with less hair loss at 4 weeks after the last dose of chemotherapy, and quality of life measures were significantly better 1 month after the end of chemotherapy in the scalp cooling group.
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TLDR
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