Management and outcome of metastatic pheochromocytomas/paragangliomas: an overview

  title={Management and outcome of metastatic pheochromocytomas/paragangliomas: an overview},
  author={G. De Filpo and M. Maggi and M. Mannelli and L. Canu},
  journal={Journal of Endocrinological Investigation},
  • G. De Filpo, M. Maggi, +1 author L. Canu
  • Published 2020
  • Medicine
  • Journal of Endocrinological Investigation
  • Background Metastatic pheochromocytomas and paragangliomas (PPGLs) occur in about 5–26% of cases and are characterized by a heterogeneous prognosis. Metastases can be synchronous at the initial diagnosis, but they can occur also many years after surgery for the primary tumor. To date, the treatment of patients affected by metastatic PPGLs represents a clinical challenge because of the lack of guidelines. Aim The aim of this article is to review the available management options and their impact… CONTINUE READING


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