Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.

@article{Galili1988ManAA,
  title={Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.},
  author={Uri Galili and Stephen B. Shohet and Eugenia Kobrin and Cheryl L. M. Stults and Bruce Macher},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 33},
  pages={17755-62}
}
The study of the expression of alpha-galactosyl epitopes on various mammalian cells is of particular interest, since as much as 1% of circulating IgG antibodies in humans interact with this carbohydrate residue. This natural antibody, designated "anti-Gal," was previously found to bind to terminal Gal alpha 1----3Gal beta 1----4GlcNAc-R on biochemically defined glycolipids (Galili, U., Macher, B. A., Buehler, J., and Shohet, S. B. (1985) J. Exp. Med. 162, 573-582; Galili, U., Buehler, J… CONTINUE READING

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