SHOWING 1-10 OF 30 REFERENCES
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study
- Autism research : official journal of the International Society for Autism Research
Maternal use of acetaminophen in pregnancy was associated with ASD with hyperkinetic symptoms only, suggesting acetaminphen exposure early in fetal life may specifically impact this hyperactive behavioral phenotype. Expand
Association Between Prenatal Acetaminophen Exposure and Future Risk of Attention Deficit/Hyperactivity Disorder in Children
- The Annals of pharmacotherapy
There does appear to be a mild correlation between prenatal acetaminophen use and the development of ADHD symptoms in children, but current data do not provide sufficient evidence that prenatalacetaminophen exposure leads to development of stimulant symptoms late in life. Expand
Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders.
- JAMA pediatrics
Maternal acetaminophen use during pregnancy is associated with a higher risk for HKDs and ADHD-like behaviors in children and because the exposure and outcome are frequent, these results are of public health relevance but further investigations are needed. Expand
Associations between Acetaminophen Use during Pregnancy and ADHD Symptoms Measured at Ages 7 and 11 Years
- PloS one
Findings strengthen the contention that acetaminophen exposure in pregnancy increases the risk of ADHD-like behaviours and supports earlier claims that findings are specific to acetamine. Expand
Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro.
- Human reproduction
First evidence that direct exposure to mild analgesics can result in multiple endocrine disturbances in the human adult testis is provided, particularly in high-risk population subgroups such as elite athletes. Expand
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
- The Journal of clinical endocrinology and metabolism
It is suggested that the fetal human testis displays slight critical age windows for sensitivity to direct exposure to aspirin, indomethacin, and paracetamol, and analgesics at concentrations relevant to human exposure cause endocrine disturbances in the fetal testis. Expand
Prenatal and perinatal analgesic exposure and autism: an ecological link
- Environmental Health
This ecological analysis identified country-level correlations between indicators of prenatal and perinatal paracetamol exposure and autism/ASD and mechanistic evidence suggest the need for formal study of the role of par acetamol in autism. Expand
Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study.
- International journal of epidemiology
Children exposed to long-term use of paracetamol during pregnancy had substantially adverse developmental outcomes at 3 years of age, and Ibuprofen exposure was not associated with neurodevelopmental outcomes. Expand
Acetaminophen may mediate oxidative stress and neurotoxicity in autism.
- Medical hypotheses
Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems
- Chemistry, Medicine
- Journal of neuroendocrinology
EDCs, from varied sources, may have organisational effects during development and/or activational effects in adulthood that influence sexually‐dimorphic, reproductively‐relevant processes or other functions, by mimicking, antagonising or altering steroidal actions. Expand