Mammographic density and the risk and detection of breast cancer.

  title={Mammographic density and the risk and detection of breast cancer.},
  author={Norman F. Boyd and Helen Guo and Lisa J. Martin and Limei Sun and Jennifer Stone and Eve Fishell and Roberta A. Jong and Gregory T Hislop and Anna M. Chiarelli and Salomon Minkin and Martin Joel Yaffe},
  journal={The New England journal of medicine},
  volume={356 3},
BACKGROUND Extensive mammographic density is associated with an increased risk of breast cancer and makes the detection of cancer by mammography difficult, but the influence of density on risk according to method of cancer detection is unknown. METHODS We carried out three nested case-control studies in screened populations with 1112 matched case-control pairs. We examined the association of the measured percentage of density in the baseline mammogram with risk of breast cancer, according to… 

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