Mammary tumorigenesis in growth hormone deficient spontaneous dwarf rats; effects of hormonal treatments

@article{Thordarson2004MammaryTI,
  title={Mammary tumorigenesis in growth hormone deficient spontaneous dwarf rats; effects of hormonal treatments},
  author={Gudmundur Thordarson and Sheila J Semaan and Caroline Low and Dafne Ochoa and Harriet Leong and Lakshmanaswamy Rajkumar and Raphael C. Guzman and S. B. Nandi and Frank J Talamantes},
  journal={Breast Cancer Research and Treatment},
  year={2004},
  volume={87},
  pages={277-290}
}
This study was carried out to investigate mammary tumorigenesis in growth hormone (GH) deficient spontaneous dwarf rats (SDR). At 50–60 days of age, the rats were divided into five groups. Group 1 received bovine (b) GH (prolonged release formulation) administered at a dose of 40–50 mg/kg body wt. in 50 μl weekly injections; group 2 received recombinant human insulin-like growth factor-I (IGF-I) at a dose of 1 mg/kg body wt./day administered via osmotic pumps; animals in group 3 were fitted… CONTINUE READING
21 Citations
51 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Similar Papers

Loading similar papers…