Mammary cancer resistance and precocious mammary differentiation in the WKY rat: identification of 2 quantitative trait loci.

@article{Lella2007MammaryCR,
  title={Mammary cancer resistance and precocious mammary differentiation in the WKY rat: identification of 2 quantitative trait loci.},
  author={Virginie Lella and Daniel Stieber and Mich{\`e}le Rivi{\`e}re and Josiane Szpirer and Claude Szpirer},
  journal={International journal of cancer},
  year={2007},
  volume={121 8},
  pages={1738-43}
}
The COP and WKY rat strains are resistant to mammary cancer. It has shown previously that upon chemical carcinogen treatment, COP females exhibit mammary preneoplastic lesions which disappear within a few weeks. We show here that in similar conditions, WKY females do not exhibit any visible preneoplastic lesions. WKY females are characterized by precocious… CONTINUE READING