Mammary and vaginal myofibroblastomas are genetically related lesions: fluorescence in situ hybridization analysis shows deletion of 13q14 region.

@article{Magro2012MammaryAV,
  title={Mammary and vaginal myofibroblastomas are genetically related lesions: fluorescence in situ hybridization analysis shows deletion of 13q14 region.},
  author={Gaetano Magro and Alberto Righi and Laura Casorzo and Torrisi Antonietta and Lucia Salvatorelli and Denisa Kacerovsk{\'a} and Dmitry W Kazakov and Michael Michal},
  journal={Human pathology},
  year={2012},
  volume={43 11},
  pages={1887-93}
}
Partial monosomy 13q, a chromosomal alteration originally reported in spindle cell lipoma, has also been documented in a few cases of mammary myofibroblastoma. Subsequently, a monoallelic loss of RB1 and FOXO1, located on 13q14, was identified in some cases of cellular angiofibroma, a benign stromal tumor of the lower female genital tract. This cytogenetic… CONTINUE READING