Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony.

Abstract

The mammalian target of rapamycin (mTOR) protein kinase responds to diverse environmental cues to control a plethora of cellular processes. mTOR forms the catalytic core of at least two distinct signaling complexes known as mTOR complexes 1 and 2. Differing sensitivities to the mTOR inhibitor rapamycin, unique partner proteins, distinct substrates, and… (More)
DOI: 10.1074/jbc.R109.094003

Topics

2 Figures and Tables