Mammalian stanniocalcins and cancer.

@article{Chang2003MammalianSA,
  title={Mammalian stanniocalcins and cancer.},
  author={Andy C-M Chang and D A Jellinek and Roger R Reddel},
  journal={Endocrine-related cancer},
  year={2003},
  volume={10 3},
  pages={
          359-73
        }
}
Stanniocalcin (STC) is a glycoprotein hormone that is secreted by the corpuscle of Stannius, an endocrine gland of bony fish, and is involved in calcium and phosphate homeostasis. The related mammalian proteins, STC1 and STC2, are expressed in a wide variety of tissues. The ovaries have the highest level of STC1, and this increases during pregnancy and lactation. STC1 is present in breast ductal epithelium, and its expression is induced by BRCA1, a tumor suppressor gene that has an important… CONTINUE READING

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The role of Stanniocalcin-1 in vascular cell function

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