Mammalian retinal horizontal cells are unconventional GABAergic neurons.

  title={Mammalian retinal horizontal cells are unconventional GABAergic neurons.},
  author={Sercan Deniz and Eric Wersinger and Yannick Schwab and C Mura and Ferenc Erd{\'e}lyi and G{\'a}bor Szab{\'o} and Alvaro Rend{\'o}n and Jos{\'e}-Alain Sahel and Serge Picaud and Michel Roux},
  journal={Journal of neurochemistry},
  volume={116 3},
Lateral interactions at the first retinal synapse have been initially proposed to involve GABA by transporter-mediated release from horizontal cells, onto GABA(A) receptors expressed on cone photoreceptor terminals and/or bipolar cell dendrites. However, in the mammalian retina, horizontal cells do not seem to contain GABA systematically or to express membrane GABA transporters. We here report that mouse retinal horizontal cells express GAD65 and/or GAD67 mRNA, and were weakly but consistently… CONTINUE READING
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