Mammalian oocyte growth and development in vitro.

  title={Mammalian oocyte growth and development in vitro.},
  author={John J. Eppig and Marilyn O'Brien and Karen Wigglesworth},
  journal={Molecular reproduction and development},
  volume={44 2},
This paper is a review of the current status of technology for mammalian oocyte growth and development in vitro. It compares and contrasts the characteristics of the various culture systems that have been devised for the culture of either isolated preantral follicles or the oocyte-granulosa cell complexes form preantral follicles. The advantages and disadvantages of these various systems are discussed. Endpoints for the evaluation of oocyte development in vitro, including oocyte maturation and… CONTINUE READING


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