Mammalian defensins in the antimicrobial immune response

@article{Selsted2005MammalianDI,
  title={Mammalian defensins in the antimicrobial immune response},
  author={M. Selsted and A. Ouellette},
  journal={Nature Immunology},
  year={2005},
  volume={6},
  pages={551-557}
}
Defensins are peptidic components of the innate immune system of plants and animals. In mammals, defensins have evolved to have a central function in the host defense properties of granulocytic leukocytes, mucosal surfaces, skin and other epithelia. This review focuses on the biological functions of three structural subgroups of mammalian defensins and the evidence for their involvement as effectors of antimicrobial innate immunity. 
1,060 Citations
Defensins in innate antiviral immunity
  • 403
  • PDF
Defensins in innate immunity
  • 218
  • Highly Influenced
A pocket guide to explorations of the defensin field.
  • M. Selsted
  • Biology, Medicine
  • Current pharmaceutical design
  • 2007
  • 9
  • PDF
Defensins as anti-infective and immunomodulatory agents
  • 2
Antimicrobial peptides: natural effectors of the innate immune system
  • 188
Defensins in Viral Infections
  • 76
The mode of antifungal action of plant, insect and human defensins
  • 175
Cell adhesion properties of human defensins.
  • 3
Cationic host defense (antimicrobial) peptides.
  • 693
  • PDF
Defensins in Ulcerative Colitis
  • 1
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 118 REFERENCES
Defensins: antimicrobial peptides of innate immunity
  • T. Ganz
  • Biology, Medicine
  • Nature Reviews Immunology
  • 2003
  • 2,047
  • PDF
Mammalian defensins in immunity: more than just microbicidal.
  • 659
Primate defensins
  • R. Lehrer
  • Medicine
  • Nature Reviews Microbiology
  • 2004
  • 329
β-Defensin 1 Contributes to Pulmonary Innate Immunity in Mice
  • 230
  • PDF
β-Defensins in Lung Host Defense
  • 239
Mouse neutrophils lack defensins.
  • 217
  • PDF
A peptide antibiotic from human skin
  • 1,302
...
1
2
3
4
5
...