Mammalian defensins in immunity: more than just microbicidal.

@article{Yang2002MammalianDI,
  title={Mammalian defensins in immunity: more than just microbicidal.},
  author={D. Yang and A. Biragyn and L. Kwak and J. Oppenheim},
  journal={Trends in immunology},
  year={2002},
  volume={23 6},
  pages={
          291-6
        }
}
Mammalian defensins are small, cationic, antimicrobial peptides encoded by the host that are considered to be important antibiotic-like effectors of innate immunity. By using chemokine receptors on dendritic cells and T cells, defensins might also contribute to the regulation of host adaptive immunity against microbial invasion. Defensins have considerable immunological adjuvant activity and linkage of beta-defensins or selected chemokines to an idiotypic lymphoma antigen has yielded potent… Expand
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