Mammalian G proteins and their cell type specific functions.

  title={Mammalian G proteins and their cell type specific functions.},
  author={Nina Wettschureck and Stefan Offermanns},
  journal={Physiological reviews},
  volume={85 4},
Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple subforms of G proteins together with receptors, effectors, and various regulatory proteins represent the components of a highly versatile signal transduction system. G protein-mediated signaling is employed by virtually all cells in the mammalian organism and is centrally involved in diverse physiological functions such… CONTINUE READING
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