Mammalian Comparative Sequence Analysis of the Agrp Locus

Abstract

Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance. The molecular mechanisms underlying Agrp regulation, however, remain poorly defined. Using a combination of transgenic and… (More)

6 Figures and Tables

Topics

  • Presentations referencing similar topics