Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord.

@article{Saba2003MammalianBC,
  title={Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord.},
  author={Rie Saba and Norio Nakatsuji and Tetsuichiro Saito},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2003},
  volume={23 6},
  pages={1987-91}
}
Commissural neurons in the spinal cord project their axons through the floor plate using a number of molecular interactions, such as netrins and their receptor DCC (deleted in colorectal cancer). However, the molecular cascades that control differentiation of commissural neurons are less characterized. A homeobox gene, MBH1 (mammalian BarH1) was expressed specifically in a subset of dorsal cells in the developing spinal cord. Transgenic mice that carried lacZ and MBH1-flanking genome sequences… CONTINUE READING
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Mammalian Bar-class homeobox genes

  • T Saito, T Hama, R Saba, N Nakatsuji
  • Soc Neurosci Abstr
  • 2000
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