Mamillary Body Lesions in Monkeys Impair Object-in-Place Memory: Functional Unity of the Fornix-Mamillary System

@article{Parker1997MamillaryBL,
  title={Mamillary Body Lesions in Monkeys Impair Object-in-Place Memory: Functional Unity of the Fornix-Mamillary System},
  author={A. Parker and David Gaffan},
  journal={Journal of Cognitive Neuroscience},
  year={1997},
  volume={9},
  pages={512-521}
}
Six monkeys were trained preoperatively in an automated object-in-place memory task in which they learned 20 new scenes in each daily session. Three of the six monkeys then received stereotaxically guided bilateral mamillary body lesions, leaving the fornix intact, while the other three received a control operation. Postoperatively the control animals' rate of learning new scenes was unchanged, but the animals with mamillary body lesions showed a severe impairment, equal to that seen in… CONTINUE READING
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