Malonylniphimycin: macrolide antibiotic from Streptomyces hygroscopicus B-7: physico-chemical properties and structure elucidation.


liters of the production medium consisting of glucose 1.0%, soybeanmeal 1.0%,NaCl0.5% andCaCO3 0.1%, pH 7.0 before autoclaving. After 120 hours of cultivation at 30°C, the culture broth (4.0 liters) was centrifuged. The mycelium was extracted three times with MeOH,while the filtrate with ?7-BuOH.The active solvent extracts were combinedand evaporated to… (More)


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