Malondialdehyde-Acetaldehyde-Adducted Surfactant Protein Alters Macrophage Functions Through Scavenger Receptor A.

@article{Sapkota2016MalondialdehydeAcetaldehydeAdducte,
  title={Malondialdehyde-Acetaldehyde-Adducted Surfactant Protein Alters Macrophage Functions Through Scavenger Receptor A.},
  author={Muna Sapkota and Kusum K Kharbanda and Todd A Wyatt},
  journal={Alcoholism, clinical and experimental research},
  year={2016},
  volume={40 12},
  pages={
          2563-2572
        }
}
BACKGROUND Reactive aldehydes such as acetaldehyde and malondialdehyde generated as a result of alcohol metabolism and cigarette smoke exposure lead to the formation of malondialdehyde-acetaldehyde-adducted proteins (MAA adducts). These aldehydes can adduct to different proteins such as bovine serum albumin and surfactant protein A or surfactant protein D (SPD). Macrophages play an important role in innate immunity, but the effect of MAA adducts on macrophage function has not yet been examined… CONTINUE READING
BETA

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