Malignant tumor of the retinal pigment epithelium with extraocular extension in a phthisical eye

@article{Loeffler1996MalignantTO,
  title={Malignant tumor of the retinal pigment epithelium with extraocular extension in a phthisical eye},
  author={Karin U. Loeffler and Tero Kivehi and H. Borgmann and Heinrich Witschel},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={1996},
  volume={234},
  pages={S70-S75}
}
• Background: Malignant tumors of the retinal pigment epithelium (RPE) are exceedingly rare. We describe the histopathologic and immunohistochemical features of a RPE neoplasm that was found accidentally in a blind and painful phthisical eye. • Methods: The enucleated eye was investigated by light microscopy, and tumor tissue was also studied by electron microscopy. Immunohistochemistry was performed using antibodies against HMB-45, S-100 protein, NSE, cytokeratins, vimentin, desmin, GFAP, the… CONTINUE READING

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