Malignant transformation of a nasopharyngeal angiofibroma.

  title={Malignant transformation of a nasopharyngeal angiofibroma.},
  author={Miro S. Makek and James C. Andrews and Ugo Fisch},
  journal={The Laryngoscope},
  volume={99 10 Pt 1},
The malignant transformation of a nasopharyngeal angiofibroma is a rare occurrence. This report describes the development of a fibrosarcoma in a patient over a 20-year period after four surgical procedures and two courses of radiation therapy to control a nasopharyngeal angiofibroma. A review of the literature revealed similar descriptions of this problem. Radiation likely plays a major role in causing the malignant change. An initial complete surgical excision can prevent recurrence of a… CONTINUE READING

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