Malignant transformation in non-irradiated recurrent respiratory papillomatosis.

  title={Malignant transformation in non-irradiated recurrent respiratory papillomatosis.},
  author={David Solomon and Richard P. Smith and Haskins K. Kashima and Brigid G. Leventhal},
  journal={The Laryngoscope},
  volume={95 8},
The clinical, radiographic and post mortem findings occurring in a 6-year-old female with a four-year history of recurrent respiratory papillomatosis (RRP) are described. At autopsy, there were two separate foci of malignant transformation (malignant degeneration) in the bronchioloalveolar papillomata. This patient is the youngest in whom such changes have been described. Malignant transformation is a rare occurrence and is usually seen in older patients with longstanding papillomatosis… CONTINUE READING
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