Malignant transformation in craniopharyngiomas.


BACKGROUND Craniopharyngiomas are successfully managed with surgery and/or adjuvant chemoradiotherapy but have been documented to undergo malignant transformation (MT), albeit very rarely, with only 23 reported cases. The exact cause and pathogenesis of this MT are unknown, although the literature has suggested a possible correlation with radiotherapy… (More)
DOI: 10.1227/NEU.0000000000000380