Malignant rhabdoid tumor: a highly malignant childhood tumor with minimal karyotypic changes.

@article{Douglass1990MalignantRT,
  title={Malignant rhabdoid tumor: a highly malignant childhood tumor with minimal karyotypic changes.},
  author={Edwin C. Douglass and Marcus Valentine and Sara Rowe and David M. Parham and Judith A. Wilimas and John M Sanders and Peter James Houghton},
  journal={Genes, chromosomes & cancer},
  year={1990},
  volume={2 3},
  pages={210-6}
}
Malignant rhabdoid tumors (MRT) are rare; thus very few cytogenetic studies of this type of tumor have been performed. We report the results of cytogenetic studies of 10 MRTs from various anatomic primary sites. Six cases had normal diploid karyotypes with no detectable rearrangements or aneuploidy except for occasional tetraploid cells. In 4 of these cases the tumor phenotype was verified by electron microscopic studies. In a seventh case only normal cells were identified in short-term culture… CONTINUE READING