Malignant profile detected by CT angiographic information predicts poor prognosis despite thrombolysis within three hours from symptom onset.

@article{Puetz2010MalignantPD,
  title={Malignant profile detected by CT angiographic information predicts poor prognosis despite thrombolysis within three hours from symptom onset.},
  author={Volker Puetz and Imanuel Dzialowski and Michael D Hill and Nikolai Steffenhagen and Shelagh B Coutts and Christine M O'Reilly and A M Demchuk},
  journal={Cerebrovascular diseases},
  year={2010},
  volume={29 6},
  pages={584-91}
}
OBJECTIVE A malignant profile of early brain ischemia has been demonstrated in the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) trial. Patients with a malignant profile had a low chance for an independent functional outcome despite thrombolysis within 3-6 h. We sought to determine whether CT angiography (CTA) could identify a malignant imaging profile within 3 h from symptom onset. METHODS We studied consecutive patients (04/02-09/07) with anterior… CONTINUE READING

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