Malignant genome reprogramming by ATAD2.

Abstract

BACKGROUND Unscheduled expression of critical cellular regulators could be central to malignant genome reprogramming and tumor establishment. One such factor appears to be ATAD2, a remarkably conserved protein normally predominantly expressed in germ cells but almost systematically over-expressed in a variety of unrelated cancers. The presence of a… (More)
DOI: 10.1016/j.bbagrm.2013.06.003

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