Malignant catatonia--a continuing reality.

@article{Singerman1994MalignantCC,
  title={Malignant catatonia--a continuing reality.},
  author={B Singerman and R. K. Raheja},
  journal={Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists},
  year={1994},
  volume={6 4},
  pages={259-66}
}
A comprehensive review of the world literature confirms that malignant catatonia continues to occur and is reported and discussed in psychiatric community. It is associated with affective disorders as well as schizophrenia. The pathophysiology is still unclear but most reports suggest a hypodopaminergic state. Its reported mortality has declined from 75-100% in the preneuroleptic era to 31% during the review period (1986-1992). Bomocriptine, dantrolene, and benzodiazepines have been used with… CONTINUE READING

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