Malignant MCA Stroke: an Update on Surgical Decompression and Future Directions.

@article{Maciel2015MalignantMS,
  title={Malignant MCA Stroke: an Update on Surgical Decompression and Future Directions.},
  author={Carolina B. Maciel and Kevin N Sheth},
  journal={Current atherosclerosis reports},
  year={2015},
  volume={17 7},
  pages={40}
}
Despite a decline over the past decade in overall stroke mortality, hemispheric strokes retain a strikingly high mortality due to their potential for malignant edema and herniation. The pathogenesis of ischemic cerebral edema is steered by disruption of ionic homeostasis in the neurogliovascular unit. Significant effort has been made to identify potential medical therapies targeting edema formation with promising results. To date, decompressive craniectomy remains the therapy with the most… CONTINUE READING

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