Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner

@inproceedings{Pan2015MalibatolAR,
  title={Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner},
  author={Jie Pan and Jiali Jin and Hui-ming Ge and Kai-lin Yin and Xiang Chen and Li-juan Han and Yan Chen and Lai Qian and Xiao-xi Li and Yun Xu},
  booktitle={Journal of Neuroinflammation},
  year={2015}
}
Activation of microglia plays a crucial role in immune and inflammatory processes after ischemic stroke. Microglia is reported with two opposing activated phenotypes, namely, classic phenotype (M1) and the alternative phenotype (M2). Inhibiting M1 while stimulating M2 has been suggested as a potential therapeutic approach in the treatment of stroke. In this study, we indicated that a novel natural anti-oxidant extracted from the Chinese plant Hopea hainanensis, malibatol A (MA), decreased the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS